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RECEPTOL and Allergies

Question and Answer
17th March 2005

What is the purpose of this RECEPTOL Question and Answer Discussion?

In our first discussion towards the later part of last year, we introduced RECEPTOL® and talked about its general application to good health and well-being. Tonight, we want to go a little further and start talking about specific conditions that RECEPTOL® can help with, by taking information from the public domain. In future conference calls we hope to discuss other conditions that RECEPTOL® can help with, but tonight we are going to talk about Allergies, what are they, how do they affect us, and what we can do to prevent allergies making a mess of our lives, using traditional treatments as well as understanding the unstable biochemical mechanisms in our bodies that are caused by allergens and how RECEPTOL® balances these chemical processes out.

Now beware, that for ‘us' to make some sort of link between RECEPTOL® and allergies, we have to use some medical terminologies to describe the processes going on in our bodies. We can't just make these comments about allergies without substantiating our words.

What are allergies?

Allergies are caused by an oversensitive immune system, which leads to a misdirected immune response. The immune system normally protects the body against harmful substances, such as bacteria and viruses. In contrast, an allergic reaction is when the immune system reacts to substances (allergens) that are generally harmless and in most people do not cause an immune response.

What are these allergens?

Some of the most common allergens are:

  • dust mites (tiny insects that live in dust) a protein found in the dander (dry skin), saliva (spit), or other things from some animals
  • grass, flower, and tree pollen (the fine dust from plants)
  • mold and mildew (small living things that grow in damp places)
  • foods, such as milk, wheat, soy, eggs, nuts, seafood, and legumes which include peas, beans, and peanuts, or
  • latex

However, these inhaled allergens are our topic of discussion.

OK, so what are these inhaled allergies causes by?

The most common inhaled allergen is dust! More precisely, dust mites and their wastes (every house has them, no matter how clean), and during spring time pollen i.e. hayfever is more predominant.

As an aside, symptoms are generally worst in the early morning, for 2 reasons:

  • pollen counts are highest
  • you've been sleeping for hours in a room filled with dust and/or mold

What happens in the body during an-allergic reaction?

In a person with allergies, the first exposure to the allergen triggers the immune system to recognize the substance. Any exposure after that will usually result in symptoms.

When an allergen enters the body of a person with a sensitized immune system, histamine and other chemicals are released by certain cells. This causes itching, swelling, mucus production, muscle spasms, hives, rashes, and other symptoms.

In its attempt to protect the body, it creates specific IgE antibodies to that food. The next time the individual is exposed to that airborne allergen, the immune system releases massive amounts of chemicals and histamines in order to protect the body. These chemicals trigger a cascade of allergic symptoms that can affect the respiratory system, gastrointestinal tract, skin, or cardiovascular system.

What are the common symptoms of a reaction?

Symptoms vary in severity from person to person. Most people have symptoms that cause discomfort without being life-threatening. A few people have life-threatening reactions (called anaphylaxis).

Symptoms range from a tingling sensation in the mouth, swelling of the tongue and the throat, difficulty breathing, hives, vomiting, abdominal cramps, diarrhea, CLEAR runny nose and sneezing, itchy or stuffed nose, itchy and runny eyes, lethargy, asthma drop in blood pressure, loss of consciousness, to death. Symptoms typically appear within minutes to two hours after the person has been exposed to the allergen which he or she is allergic.

What is the best treatment for allergies?

Your doctor will probably suggest ways to stay away from the allergen or prescribe a medicine for you to try. Allergy medicine can be pills, liquids, or even sprays for your nose. If your allergies aren't too bad or if you can avoid the allergen completely, you might not need to take medicine - staying away from the allergen might be enough to control your allergy.

If your symptoms don't get better by staying away from allergens and taking medicines, an allergist might recommend allergy shots. These shots make your immune system less sensitive to the allergens and can make your symptoms better.

Is there a cure for allergies?

Currently, there are no medications that ‘cure' allergies, but various treatments including anti-histamine drugs and Mast Cell Stabilizers are used to relieve symptoms. However, strict avoidance of allergens is the only way to prevent a reaction.

How do these drugs relieve allergy symptoms?

Firstly, anti-histamines are just that, they block to histamine chemicals that are produced from a IgE covered host or mast cells in an allergic reaction, rendering them inactive. So that is anti-histamines.

Secondly, Mast-cell stabilizers are another allergy medication option. These medications work by preventing mast cells from setting the allergic reaction into action. A mast cell can be thought of as a balloon filled with chemical mediators: when an allergy-causing pollen attacks, the mast cell bursts, releasing numerous chemicals. Among these chemicals are histamine and many others that contribute to itching, redness, and swelling. A mast-cell stabilizer that keeps all of those chemicals from spilling out can be extremely helpful in preventing an allergic reaction from starting. However, it must be used before the allergic reaction occurs.

Finally, in more severe allergic reactions, adrenaline based drugs, are the best type of medications of choice.

What are the alternatives to these current drug treatments for allergic reactions?

Various allergy and asthma universities and research centers in Europe and the United States are investigating the option of modulating cytokine levels in the body during an allergic reaction. It is well understood that these cytokine levels become unstable during allergic reactions and may be the triggers that produce these allergy symptoms. If it would be possible to stabilize these cytokine levels it may reduce or eliminate allergy symptoms.

RECEPTOL has Proline-Rich Polypeptides that are used in the production of many-many cytokines such as TNF-alpha that modulate cytokine levels and thus indirectly aids in the natural control of cytokine production, which has an effect on our immune system.

It has been realized early on that manipulation of the cytokine network may interfere selectively with specific functions. This prospect has created a lot of excitement and scientists are working on many different applications. RECEPTOL is just that. It modulates or stabilizes an overactive or suppressed immune system by ‘normalizing' the cytokine levels in the body. Various laboratories have investigated INTERLEUKIN4 and other cytokines which are involved in allergy and asthma.

What are these cytokines?

Cytokines are soluble proteins which are predominantly produced by cells of the immune system. They are related to hormones, but have usually local rather than systemic functions. Immune cells communicate with each other and with the surrounding tissue by secreting cytokines, and by expressing receptors which allow themselves to get stimulated by cytokines. The cytokine network is an important communication system involved in regulating and coordinating immunity.

What cytokines are altered during an allergic reaction?

Allergy develops if a particular cytokine is produced while an allergen enters the body and the body recognizes this foreign invader. If this cytokine, called ‘interleukin-4' is present during such a contact, an allergic immune response is initiated. The immune system gets is right most of the time and nearly all people react against parasites and ignore allergens, but those who react in this way to an allergen develop allergy against this specific stimulus. Allergen plus INTERLEUKIN4 leads to allergy.

However, INTERLEUKIN4 is not the only important cytokine in allergy. INTERLEUKIN13 is unable to shift the immune system towards allergy. In many cases INTERLEUKIN13 is even the more important cytokine, since it is produced for a longer time and to higher levels than INTERLEUKIN4. Since INTERLEUKIN4 and INTERLEUKIN13 are important for maintaining and organizing allergic immunity, an inhibitor would be expected to be therapeutically useful. A cytokine modulator, such as RECEPTOL, naturally can modulate the instability in these Interleukin-4 and Interleukin-13 levels.

What scientific studies have validated these ideas?

In controlled laboratory animal models with mice have suggested that inhibiting INTERLEUKIN-4/INTERLEUKIN-13 is useful in reducing the symptoms of asthma. Scientists have shown that controlling the levels of mouse INTERLEUKIN-4 completely prevented allergic sensitization in a non-asthma situation. Now scientists are trying to use cytokine inhibition for curing rather then preventing allergies. RECEPTOL®, a peptide-based cytokine inhibitor, can suppress these INTERLEUKIN-4/INTERLEUKIN-13 levels and suppress over-reactive immune system that lead to allergy symptoms.

What human models have validated these ideas?

Many anecdotal and testimonial reports have indicated that RECEPTOL® can help reduce the symptoms of allergies. For example, many reported cases within the GLOBALCEUTICALS INT'L INC. family have shown to have their allergy symptoms relieved. In fact the first observable health benefit in taking RECEPTOL® is the relief of allergies. Generally, we can hear about all the scientific mechanisms of how RECEPTOL® works in the body, but until people experience these benefits themselves, people are usually not convinced.

Are there any other cytokines and processes involving cytokines involved with allergies in humans and mammals?

Yes. INTERLEUKIN-4 and INTERLEUKIN-13 are by no means the only cytokines involved in allergy. Other relevant factors are for example INTERLEUKIN-5, which is responsible for asthmatic symptoms, and INTERLEUKIN-9, which is enhancing many disease-associated features of asthma. A special class of cytokines are the chemokines, these attract inflammatory compounds into the tissue, and cooperate to organize inflammatory processes in asthma.

We are interested to understand the molecular interaction between pollutants and the immune system. We could indeed show that specific substances from the group of polycyclic aromatic hydrocarbons especially in city centers, commonly called SMOG, are able to up-regulate expression of INTERLEUKIN-4. Scientists now are continuing their investigations of several other cytokine and chemokine promoters for effects of these components.

Understanding these mechanisms in polluted city centers would allow to further identify which substances in pollutant particles are actually interfering with immune function, and may require monitoring and regulation. The identification of new molecular mechanisms for modulating expression of chemokines and cytokines may even reveal new targets for therapeutic manipulation of the cytokine network, especially in asthmatic persons in urban centers.

Aside from all this heavy chemistry about cytokines, what do you think is going to happen in the next few years in the application of natural products such as RECEPTOL® to specific health conditions?

Basically, as far as I can see, three things will happen in the next few years.

  1. We will keep the status-quo in pumping trillions of dollars into dealing with peoples health problems with synthetic or biochemical drugs, or
  2. The big companies will start incorporating more and more natural products in there drug production, as long as they can protect their intellectual property, or
  3. Natural products will become more and more used to help people with their health concerns, as long as there is enough clinical data to support their structure and function claims.

Scientists are currently working on developing new synthetic drug systems that stabilize cytokine function...that's right synthetic chemicals produced in a test tube to artificially suppress the symptoms of allergies and asthma. These artificial drugs can be detrimental to our health of you take enough of them for extended periods of time.

We all know the fine print that you get when you get a medication for a particular ailment, it tells us or all the harmful things that could happen to us should we take this drug... but wait! Natures goodness that delivers natural solutions to medical diseases, is now harnessed in RECEPTOL® and we ‘may' now have the answer to Allergies, naturally, with no side effects, at least that is the consensus from the people that have taken RECEPTOL® for allergy relieve.

It tastes good and corrects the cytokine imbalances that are caused by Allergens. We spend billions of dollars looking in the wrong places from answers to our health concerns. Nature has that answer, but since you cannot hold a product patent on natures products the is not enough money in it for the big pharmaceutical companies.

Some large companies are showing an interest in using natural products, which is promising, but they would not say that they are getting them from nature or everybody else will start to copy it. However, it is important in GLOBALCEUTICALS INT'L INC. to help people with there health conditions as cheaply as possible. Let's get back into the mode of helping people with their health rather than help them unload the money in there pockets.

So get your RECEPTOL® today and help treat allergies...naturally.

Do you have any final comments about RECEPTOL and Allergies?

Currently, RECEPTOL® is the only peptide product that can modulate cytokine levels in the human body and mammals.

RECEPTOL® not only helps with Allergies but remember RECEPTOL® has wide ranging health benefits to us all. Just take the spray twice a day and you should feel better throughout the day. It's inexpensive but effective. The GLOBALCEUTICALS INT'L INC. philosophy is to help all of us with our own health conditions, and do this naturally and inexpensively. Nature already has the answers to our health problems, now that scientists are continuing to find these answers in nature lets all get well and enjoy our lives.

Z LIFE FAQs


Q: What is zeolite?
A: Zeolite is a unique mineral, which is a crystalline microporous element that is both naturally occurring and synthetically produced. Because it is one of the few negatively charged minerals on earth, it has the ability to magnetize positively charged metals into its honeycomb structure. It acts like a collection agent removing unwanted toxic metals from the body to eliminate them through the various elimination systems in the body.


Q: What is Z LIFE?
A: Z-LIFE is zeolite delivered in a bed of humic acid. Through proprietary advanced technology, the humic molecule ingests the zeolite mineral consequently birthing a highly stable and potent survival food. Z LIFE® is a natural (not synthetic) volcanic zeolite (clinoptilolite) processed without harsh chemicals in a base of humic acid and structured water. Z LIFE® represents one of the greatest and most exciting scientific achievements currently in the marketplace today. Through a proprietary process, humic acid is organically induced to absorb the zeolite directly into its molecular structure making it more effective than any other method.

Q: Tell me more?
A: Some other forms of liquid zeolite are made using harsh and toxic chemical reagents. The zeolite in Z LIFE® has been naturally and organically placed into humic acid (an organic carrier) and is now a unique component of the humic molecule. The end result is an all natural, completely pure product that can be carried directly into the cellular structure of our bodies.
Zeolite and humic very successfully help remove
heavy metals and toxins from the body.
 
Q: What is the humic acid in Z-LIFE?

A: Humic Acids are biological compounds created by Mother Earth. We call it “mother’s milk from the earth.” These composites were originally deposited by pristine, ancient forests and compacted and transformed over millions of years, waiting to be extracted for our use today.
The roots of humic acid originate in early Native American traditions. Combining modern technological advances with this divine gift from nature results in this miraculous organic product that is the richest source of 100% bioavailable micro and macro mineral nutrients – as many as 70 organic ionic minerals. The pH factor of Z-LIFE reads at an impressive 7.4 to 8.0.

Humic substances are the link between the living and the nonliving in nature. They were orchestrated by Mother Nature to bridge this gap because the nutrients found in humic are not usually found in our current food sources.. Furthermore, humic acids are able to beneficially influence and guide living organisms in various, unique stages of their life and growth.

When the proper amounts of humic substances are dissolved in water, the water takes on a new form, becoming molecularly restructured. Specifically, humic acids cause water to form pyramid shaped molecules (tetrahedrons) that possess valuable, proven medicinal properties.

Q: What makes the combination of zeolite and humic more effective?
A: Zeolite by its nature is considered a complex molecule that when used alone is not easily absorbed on the cellular level. Therefore, when zeolite is chemically processed to extract the molecules in a water base or powder form, the intention of its mechanism of action is far less effective. It has long been known that humic and fulvic acids have the ability to penetrate the cell extremely well. In fact, many prescription drugs use these acids for their delivery system. Consequently, our product has been known to deliver extraordinary results in a relatively short time.

Q: Is Z LIFE® similar to Waiora’s popular Natural Cellular Defense (NCD)?
A: Yes, but only in the fact they are both liquid Zeolites. The zeolite in NCD is suspended in water and is manufactured using a high-heat chemical process. Z Life's® process induces humic acid to absorb the zeolite directly into its molecular structure at room temperature.

Q: Is zeolite safe?
A: According to worldwide studies on the over 40 zeolite elements, natural Zeolites are inert, non-toxic minerals and are under federal classification as GRAS (Generally Regarded As Safe). The zeolite we use in Z LIFE is a pure grade zeolite extracted from a privately owned mine free of possible contaminants such as heavy metals and radioactive elements.

Q: Is there any caution for the use of Z LIFE?
A: If you are taking any prescription medication containing heavy metals (lithium, platinum, etc.) it would be advised not to take Z LIFE until you are no longer on that medication. Check with your health care practitioner for full disclosure of the ingredients of your prescription drugs.

 
 

Compex Muscle Stimulator FAQs

The Best Muscle Workout from the Comfort of your Chair

 

Compex FAQs

Q. Who is the Compex Sport intended for?

A. The Compex Sport is intended for anyone who wishes to improve their body's performance.

Q. Can I train my muscles more thoroughly using Compex than by voluntary training?

A. Yes. When you stimulate a muscle with a Compex program, there is no limit on the amount of muscular work you can do, because there is no psychological or cardiovascular fatigue. The precision achievable using stimulation means that you can work your muscles in a much more localized and effective way than is possible using traditional voluntary exercise.

Q. Why is Compex training non-traumatic?

A. With Compex, muscle contractions develop progressively, placing no sudden traction on joints or tendons, so it is not possible to cause muscle or tendon trauma.

Q. How do I integrate the Compex Sport into normal training?

A. A Training Planner (on CD-ROM) that provides comprehensive operating instructions and training plans for different sporting disciplines accompanies each Compex Sport.

Q. What computer configuration is needed to run the CD-ROM?

A. Windows 95, Windows 98, Windows 2000 or Windows NT

Q. Are electrodes supplied with the stimulator unit?

A. Yes. When purchased, each stimulator includes 1 set of basic electrodes (4 small and 2 large electrodes)

Q. How long is the Compex warranty?

A. 2 years (plus 1 additional year by completing the warranty registration form)

Q. Where on the body should the electrodes be placed?

The positive electrode (red) must be placed in the region of the motor point of the muscle. The negative electrode (transparent) is placed on the course of the muscle. Your Compex Sport CD-ROM illustrates the correct placement of electrodes depending on your sport and the muscle area to be stimulated.

Q. How many times can the electrodes be used?

A. Depending on the type and condition of the skin, between 15 and 30 times. Around 30 applications are possible on skin that is clean, degreased and shaven.

Q. Does incorrect positioning of the electrodes create any risks?

A. No. There is no risk in incorrectly positioning the electrodes. The stimulation simply becomes less efficient.

Q. What intensity should be reached for training programs (strength, resistance, endurance, etc.)?

A. The highest level possible (but bearable) in order to recruit the largest possible numbers of muscle fibers. The best control mechanism is your subjective evaluation of how it feels: the contractions must be powerful without ever becoming unbearable.

Q. What intensity should be reached for special programs (potentiation, active recovery)?

A. These programs do not require the use of maximum current levels. However, the intensities must be high enough to produce vigorous muscular twitches (generally in the range of 20 and 40 mA).

Q. Can I injure myself using too high a current level?

A. No. It is not possible to injure yourself because the current is applied progressively throughout the contraction period to avoid any risk of muscle damage.

Q. Can the Compex simply replace voluntary training?

A. No. It is vital to continue regular training for your specific sports discipline. Compex training acts as a supplement to voluntary training to further enhance overall training performance.

Q. What does Compex contribute to traditional training?

A. It enables the quantity and quality of training to be increased and helps recovery. You can train better and faster: saving time and improving efficiency and performance.

Q. Can Compex sessions take place during voluntary training sessions?

A. Compex sessions can take place outside or during voluntary training. If you wish to do both at the same time, you are advised to start with voluntary training.

Q. How do I know which program to use?

A. The Training CD-ROM that comes with the Compex Sport helps you optimize your workouts and training regimen.

Q. Are there any studies that demonstrate results?

A. Yes, follow the link to our About the Technology section to browse through the numerous clinical studies and papers about E-Stim and its impact on athletic performance in numerous sports.

Q. Are Compex muscle stimulators safe to use?

A. Yes, Compex is the only muscle stimulator cleared by the FDA for sale in the US. Compex Technologies is a leader in medical technology and the use of E-Stim for medical, rehabilitation, pain control, sports and fitness enhancement purposes. The type of current used in Compex is based on medical technology and cannot cause burns.

Q. Are there any long-term risks associated with stimulation?

A. No. EMS and electrotherapy have been in general use for decades and no problems have ever been reported.

Q. Are there any absolute contra-indications?

A. Yes. The equipment must not be used by people with epilepsy or by patients fitted with a heart pacemaker. E-Stim should never be applied to the abdomens of pregnant women or to anyone suffering from a hernia or rupture. In addition, electrodes must never be applied to the head or to the area around the heart.

RECEPTOL FAQ


see also: RECEPTOL and Allergies

 

RECEPTOL® and Medical Nano-Peptides (NPs) FAQs:

Q: What is RECEPTOL®?

A:
RECEPTOL® is an oral spray derived from first milking colostrum, offering the safest and most advanced support for the immune system today.

RECEPTOL® is NOT COLOSTRUM, although it is derived from it. It is a specialized concentration of Medical Nano-Peptides (MNPs) that have been carefully separated using advanced biotechnology.

Q: What is Nanotechnology?

A: Nanotechnology is the science of the small. Nano is Greek for dwarf, and nanoscience deals with the study of molecular and atomic particles, a world that is measured in nanometers (billionths of a meter or 10-9).

Medical Nano-Peptides (MNPs)

According to researchers, Medical Nano-Peptides (MNPs) are small enough that hundreds of them could fit on the surface of a biological cell. MNPs can patrol your body; armed with knowledge and the ability to communicate what is friendly and what is foreign to your immune system, they can repel any foreign invaders by attaching themselves to specific receptor sites on the surface of the cell. Because they fill those receptor sites, foreign adverse invaders are blocked from entry. Imagine, the common cold or flu may no longer be a problem with RECEPTOL® on guard.

Q: How is RECEPTOL® administered?

A: RECEPTOL® comes in a 4.25 ounce pump-spray bottle. It is generally sprayed onto the inner cheek wall an average of three sprays two to three times per day (21 milliliters). It is advised to hold the liquid in the mouth without swallowing for at least 60 seconds or so. There are a few other recommendations depending on what the specific health challenge is.

Q: How does RECEPTOL® work?

A: By spraying RECEPTOL® on the inner cheek, Medical Nano-Peptides (1-billionth or 0.000 000 001 of a meter in size) are delivered through the mucosal membrane directly into the blood stream within seconds.

In both clinical and field observations, our theory proposes that these MNPs attach to the receptor site on T-cells imparting instruction to the immune system to reorient or correct its response strategy against autoimmune disease. This process induces anti-inflammatory cytokine-type activity by the body. In other words, we believe these MNPs essentially reboot the immune system, so the cell’s original immune response is restored. Further studies are in progress and planned in the future.

Q: So, is RECEPTOL® a cure?

A: We cannot use the term “cure.” The FDA prohibits such claims. However, we must understand that only the body can cure itself. A myriad of biological variances and the attendant responses of human beings determine whether a person can employ the effective use of whatever may be introduced into an individual’s system. The FDA even prohibits drug companies from touting that they have a cure for any condition. In actuality, most of the time drugs interfere with the wisdom of the body to repair and heal. All drugs have “side effects,” a term which is more medically acceptable than saying it is harmful. If the appropriate resource is available, the body knows what to do with it. In clinical situations with the use of RECEPTOL®, and depending on the challenge, the body can sometimes recover in a relatively short period of time.

Q: What is the mode of action?

A: We believe MNPs impart information analogous to downloading computer software. This information acts as an "operating system" directing and contributing to the cells ability to respond to pathogens while rebooting the immune system to recognize foreign versus friendly. We believe this type of information is what nature intended to deliver to the cells of infants through colostrum from the first few days of breast feeding prior to the digestive process being initiated and becoming fully functional. In RECEPTOL®, these MNPs are concentrated. (In Candace Pert's book "Molecules of Emotion", she traces her scientific journey by documenting the existence of what appears to be information carrying peptides to receptor sites throughout the body. We believe the MNPs in RECEPTOL® are consistent with her scientific findings).

Q: What are the practical applications for MNP supplementation?

A: At this time, we are conducting Phase 3 Clinical Trials in Bombay, India with the full support of the Indian Government. We are in the process of registering RECEPTOL® as a pharmaceutical drug and filing a medical use patent for HIV/AIDS in India as well. Currently, we have several cases in which RECEPTOL® proves effective for Hepatitis C (HCV). RECEPTOL® also seems to be effective for the common cold, flu, herpes, fungus, chronic fatigue, fibromyalgia, shingles, and for topical use on the skin as well as for the health of the gums.

Q: How does the body use the MNPs?

A: The MNPs are typically absorbed through the oral mucosa and are not utilized through the digestive tract. They may also be absorbed directly by cells through open tissue injuries including surgery, burns and some lesions.

Q: So, RECEPTOL® also works for animals?

A: It has been effective with species other than humans. Oral spray is easier to administer than pills. An excellent application is for the gums in animals since brushing is challenging for most.

Q: How long does someone have to take RECEPTOL®?

A: Because the variety of conditions RECEPTOL® is used for, it is difficult to determine exact timeframes. There have been cases where people have taken it for as short a duration as two weeks and have had no reoccurrence of symptoms. About 40% of the time, there is no reoccurrence of symptoms for as long as a year. About 60% of the time there can be a reoccurrence of symptoms within four to six months or so after only using RECEPTOL® for 15 to 30 days. In severe situations, it would be advisable to continue use for up to 2 years even if symptoms have disappeared.

Q: Is RECEPTOL® a drug?

A: RECEPTOL® is currently classified as a dietary supplement in the United States, but is being classified and registered as a drug in India.

Q: Does RECEPTOL® have any side effects?

A: No! There are no known side effects or contraindications. It is safe to take with anything else and is not effected by any other substance that we know of.

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